Phase II, Parallel, Randomized, Clinical Trials Comparing the Responses to Initiation of NNRTI-Based Versus PI-Based Antiretroviral Therapy in HIV-Infected Infants Who Have and Have Not Previously Received Single Dose Nevirapine for Prevention of Mother-to-Child HIV Transmission

Sponsors: US National Institute of Allergy and Infectious Diseases (NIAD)
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Protocol Summary: P1060 is designed to compare the effectiveness of a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral regimen versus a protease inhibitor (PI)-based regimen in HIV infected infants who had or had not been exposed to single dose Nevirapine for prevention of MTCT.

Years: 2007 – 2012

Investigator: Mutsawashe Bwakura-Dangarembizi, MBChB, MMED, MSc Cli.Epi

Location: Parirenyatwa CRS

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